• 12 maja, 2021
ewaagroart

Wariant genu SARS-CoV-2 E zmienia

Wariant genu SARS-CoV-2 E zmienia charakterystykę czułości analitycznej wykrywania wirusów przy użyciu komercyjnego testu RT-PCR 

Diagnostic assays for detecting SARS-CoV-2 are important for affected person administration, an infection prevention, and the general public well being response for COVID-19. The efficacy and reliability of those assays are of paramount significance in each monitoring and controlling unfold of the virus. Actual-time RT-PCR assays depend on a set genetic sequence for primers and probe binding. Mutations can probably alter the accuracy of those assays and result in unpredictable analytical efficiency traits and false-negative outcomes. Herein, we establish a G-to-U transversion (nucleotide 26372) in the SARS-CoV-2 E gene in three specimens with lowered viral detection effectivity utilizing a extensively accessible industrial assay.

Additional evaluation of the general public GISAID repository led to the identification of 18 further genomes with this mutation, which replicate 5 unbiased mutational occasions. This work helps using dual-target assays to cut back the variety of false-negative PCR outcomes.

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qPCR ProbesMasterMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-360S 2 x 1,25 ml
EUR 205
Description: qPCR ProbesMasterMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster UNGMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-363L 10 x 1,25 ml
EUR 982
Description: qPCR ProbesMaster UNGMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster UNGMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-363S 2 x 1,25 ml
EUR 246
Description: qPCR ProbesMaster UNGMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-362L 10 x 1,25 ml
EUR 818
Description: qPCR ProbesMaster highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-362S 2 x 1,25 ml
EUR 205
Description: qPCR ProbesMaster highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-361L 10 x 1,25 ml
EUR 818
Description: qPCR ProbesMaster lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-361S 2 x 1,25 ml
EUR 205
Description: qPCR ProbesMaster lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster UNG lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-364L 10 x 1,25 ml
EUR 982
Description: qPCR ProbesMaster UNG lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster UNG lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-364S 2 x 1,25 ml
EUR 246
Description: qPCR ProbesMaster UNG lowROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster UNG highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-365L 10 x 1,25 ml
EUR 982
Description: qPCR ProbesMaster UNG highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

qPCR ProbesMaster UNG highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

M-PCR-365S 2 x 1,25 ml
EUR 246
Description: qPCR ProbesMaster UNG highROXMaster mix for quantitative real-time PCR using labeled DNA probes, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

Tiamulin ELISA Kit, Quantitative

DEIA036 96T
EUR 1414.8
Description: This kit is intended for quantitative analysis of tiamulin residue in animal tissue (pork and chicken, etc).

Human RBP4 Quantitative ELISA Kit

LF-EK70030 1×96T
EUR 722.4

Rat C3 ELISA Kit, 96 tests, Quantitative

6230 1 kit
EUR 854.4

Cat IgG ELISA Kit, 96 tests, Quantitative

300-100-CGG 1 kit
EUR 854.4

Cat IgM ELISA kit 96 tests, Quantitative

300-170-CGM 1 kit
EUR 854.4

Cat IgA ELISA Kit, 96 tests, Quantitative

300-180-CGA 1 kit
EUR 854.4

Cat IgE ELISA Kit, 96 tests, Quantitative

300-190-CGE 1 kit
EUR 854.4

Dog IgG ELISA Kit, 96 tests, Quantitative

400-100-DGG 1 Kit
EUR 781.2

Dog IgM ELISA Kit, 96 tests, Quantitative

400-170-DGM 1 Kit
EUR 781.2

Dog IgA ELISA Kit, 96 tests, Quantitative

400-180-DGA 1 Kit
EUR 854.4

Dog IgE ELISA Kit, 96 tests, Quantitative

400-190-DGE 1 Kit
EUR 854.4

Rat IgG ELISA Kit, 96 tests, Quantitative

6420 1 kit
EUR 781.2

Rat IgE ELISA Kit, 96 tests, Quantitative

6470 1 kit
EUR 927.6

Rat IgM ELISA Kit, 96 tests, Quantitative

6480 1 Kit
EUR 854.4

Rat IgA ELISA kit 96 tests, Quantitative

6410-10 1 kit
EUR 607.2

Pig IgM ELISA Kit, 96 tests, Quantitative

9080 1 kit
EUR 854.4

Lactate ELISA Kit, 96 tests, Quantitative

10795 1 Kit
EUR 927.6

Rat VEGF ELISA Kit, 96 tests, quantitative

200-840-VER 1 kit
EUR 927.6

Goat IgG ELISA Kit, 96 tests, Quantitative

7520 1 kit
EUR 781.2

Goat IgM ELISA Kit, 96 tests, Quantitative

7530 1 kit
EUR 927.6

Goat IgA ELISA Kit, 96 tests, Quantitative

7540 1 kit
EUR 1000.8

Goat IgE ELISA Kit, 96 tests, Quantitative

7550 1 kit
EUR 1000.8

Rat IgG1 ELISA Kit, 96 tests, Quantitative

6430 1 Kit
EUR 854.4

Oxytocin ELISA Kit, 96 tests, Quantitative

10790 1 Kit
EUR 927.6

Human IgG ELISA Kit, 96 tests, Quantitative

1750 1 Kit
EUR 781.2

Human IgM ELISA Kit, 96 tests, Quantitative

1760 1 Kit
EUR 781.2

Human IgA ELISA Kit, 96 tests, Quantitative

1780 1 kit
EUR 781.2

Sheep IgG ELISA Kit, 96 tests, Quantitative

7620 1 Kit
EUR 781.2

Sheep IgM ELISA Kit, 96 tests, Quantitative

7630 1 kit
EUR 854.4

Sheep IgA ELISA Kit, 96 tests, Quantitative

7640 1 kit
EUR 1000.8

Sheep IgE ELISA Kit, 96 tests, Quantitative

7650 1 kit
EUR 1000.8

Horse IgA ELISA Kit, 96 tests, Quantitative

7720 1 kit
EUR 854.4

Horse IgG ELISA Kit, 96 tests, Quantitative

7730 1 kit
EUR 854.4

Horse IgM ELISA Kit, 96 tests, Quantitative

7740 1 kit
EUR 854.4

Horse IgE ELISA Kit, 96 tests, Quantitative

7750 1 kit
EUR 927.6

Camel IgG ELISA Kit, 96 tests, Quantitative

7820 1 kit
EUR 854.4

Mouse IgA ELISA Kit, 96 tests, Quantitative

6310 1 kit
EUR 781.2

Mouse IgG ELISA Kit, 96 tests, Quantitative

6320 1 kit
EUR 781.2

Mouse IgE ELISA Kit, 96 tests, Quantitative

6370 1 Kit
EUR 781.2

Mouse IgM ELISA Kit, 96 tests, Quantitative

6380 1 Kit
EUR 781.2

Rat IgG2a ELISA Kit, 96 tests, Quantitative

6440 1 Kit
EUR 578.4

Rat IgG2b ELISA Kit, 96 tests, Quantitative

6450 1 Kit
EUR 634.8

G. Pig IgA ELISA Kit, 96 tests, Quantitative

7410 1 kit
EUR 854.4

G. Pig IgG ELISA Kit, 96 tests, Quantitative

7420 1 kit
EUR 781.2

G. Pig IgM ELISA Kit, 96 tests, Quantitative

7430 1 kit
EUR 781.2

Mouse VEGF ELISA Kit, 96 tests, Quantitative

100-230-VEM 1 Kit
EUR 854.4

Vitamin A ELISA Kit, 96 tests, Quantitative

10760 1 Kit
EUR 927.6

Vitamin B1 ELISA Kit, 96 tests, Quantitative

10765 1 Kit
EUR 927.6

Vitamin C ELISA Kit, 96 tests, Quantitative

10770 1 Kit
EUR 927.6

Vitamin E ELISA Kit, 96 tests, Quantitative

10775 1 Kit
EUR 927.6

Bovine IgG ELISA Kit, 96 tests, Quantitative

8010 1 Kit
EUR 781.2

Turkey IgG ELISA Kit, 96 tests, Quantitative

8020 1 kit
EUR 781.2

Horse Fab2 ELISA Kit, 96 tests, Quantitative

7710-Fab 1 kit
EUR 854.4

Mouse IgG1 ELISA Kit, 96 tests, Quantitative

6330 1 kit
EUR 781.2

Mouse IgG3 ELISA Kit, 96 tests, Quantitative

6360 1 kit
EUR 781.2

Monkey IgA ELISA Kit, 96 tests, Quantitative

7010 1 Kit
EUR 854.4

Rabbit IgA ELISA Kit, 96 tests, Quantitative

6510 1 kit
EUR 927.6

Rabbit IgM ELISA Kit, 96 tests, Quantitative

6580 1 kit
EUR 708

Bovine IgA ELISA Kit, 96 tests, Quantitative

8075 1 Kit
EUR 854.4

Bovine IgM ELISA Kit, 96 tests, Quantitative

8080 1 Kit
EUR 854.4

Mouse CCL2 ELISA Kit, 96 tests, Quantitative

MCC-0L2-100 1 kit
EUR 578.4

Mouse CCL3 ELISA Kit, 96 tests, Quantitative

MCC-0L3-100 1 kit
EUR 607.2

Human CCL2 ELISA Kit, 96 tests, Quantitative

HCC-0L2-105 1 kit
EUR 578.4

Human CCL3 ELISA Kit, 96 tests, Quantitative

HCC-0L3-110 1 kit
EUR 578.4

Human CCL4 ELISA Kit, 96 tests, Quantitative

HCC-0L4-115 1 kit
EUR 578.4

Human CD93 ELISA Kit, 96 tests, Quantitative

HCD-093-120 1 kit
EUR 578.4

Protein-A ELISA Kit, 480 tests, Quantitative

800-110-PRA-5 1 pk
EUR 3714

Rat IL-13 ELISA Kit, 96 tests, Quantitative

RIL-013-100 1 kit
EUR 578.4

Vasopressin ELISA Kit, 96 tests, Quantitative

10800 1 Kit
EUR 927.6

Pig Insulin ELISA Kit, 96 tests, Quantitative

10420 1 Kit
EUR 927.6

Vitamin B12 ELISA kit, 96 tests, Quantitative

0340-B12 1 Kit
EUR 927.6

D-Lactate ELISA Kit, 96 tests, Quantitative

10845 1 Kit
EUR 927.6

Protein-A ELISA Kit, 96 tests, Quantitative

800-110-PRA 1 kit
EUR 927.6

Mouse IgG2a ELISA Kit, 96 tests, Quantitative

6340 1 kit
EUR 781.2

Mouse IgG2b ELISA Kit, 96 tests, Quantitative

6350 1 kit
EUR 781.2

Dog Albumin ELISA Kit, 96 tests, Quantitative

7000-50 1 kit
EUR 781.2

Chicken IgM ELISA Kit, 96 tests, Quantitative

6040 1 kit
EUR 781.2

Rat Albumin ELISA Kit, 96 tests, Quantitative

6400 1 kit
EUR 781.2

Mouse CXCL3 ELISA Kit, 96 tests, Quantitative

MCXC-003-100 1 kit
EUR 578.4

Human CXCL3 ELISA Kit, 96 tests, Quantitative

HCXC-003-100 1 kit
EUR 578.4

Human CXCL9 ELISA Kit, 96 tests, Quantitative

HCXC-090-100 1 kit
EUR 578.4

Benedicts Solution Quantitative

RRSP900-D 500ml
EUR 6.36

Benedicts Solution Quantitative

RRSP900-E 1L
EUR 10.59

Benedicts Solution Quantitative

RRSP900-F 2.5L
EUR 21.96

Mouse IL-2 ELISA Kit, 96 tests, Quantitative

MIL-002-105 1 kit
EUR 578.4

Mouse IL-4 ELISA Kit, 96 tests, Quantitative

MIL-004-110 1 kit
EUR 578.4

Mouse IL-5 ELISA Kit, 96 tests, Quantitative

MIL-005-115 1 kit
EUR 578.4

Mouse IL-9 ELISA Kit, 96 tests, Quantitative

MIL-009-120 1 kit
EUR 578.4

Human IL-4 ELISA Kit, 96 tests, Quantitative

HIL-004-105 1 kit
EUR 578.4

Human IL-5 ELISA Kit, 96 tests, Quantitative

HIL-005-110 1 kit
EUR 578.4

Human IL-9 ELISA Kit, 96 tests, Quantitative

HIL-009-115 1 kit
EUR 607.2

Human IL-8 ELISA Kit, 96 tests, Quantitative

HIL-080-170 1 kit
EUR 578.4

Rat IL-17A ELISA Kit, 96 tests, Quantitative

RIL-17A-100 1 kit
EUR 607.2

Homocysteine ELISA kit, 96 tests, Quantitative

0370-HCY 1 kit
EUR 927.6

Prostacyclin ELISA Kit, 96 tests, Quantitative

10785 1 Kit
EUR 927.6

Mouse Leptin ELISA Kit, 96 tests, Quantitative

100-130-LEM 1 Kit
EUR 854.4

Goat Insulin ELISA Kit, 96 tests, Quantitative

10730 1 Kit
EUR 927.6

Rat Glucagon ELISA Kit, 96 tests, Quantitative

9485 1 Kit
EUR 927.6

Human CXCL10 ELISA Kit, 96 tests, Quantitative

HCXC-010-100 1 kit
EUR 708

Human CXCL16 ELISA Kit, 96 tests, Quantitative

HCXC-016-100 1 kit
EUR 578.4

Bovine IL-4 ELISA Kit, 96 tests, Quantitative

BIL-004-100 1 kit
EUR 634.8

Mouse IL-10 ELISA Kit, 96 tests, Quantitative

MIL-010-125 1 kit
EUR 578.4

Mouse IL-13 ELISA Kit, 96 tests, Quantitative

MIL-013-135 1 kit
EUR 578.4

Mouse IL-21 ELISA Kit, 96 tests, Quantitative

MIL-021-155 1 kit
EUR 607.2

Mouse IL-22 ELISA Kit, 96 tests, Quantitative

MIL-022-160 1 kit
EUR 607.2

Mouse IL-23 ELISA Kit, 96 tests, Quantitative

MIL-023-165 1 kit
EUR 607.2

Mouse IL-25 ELISA Kit, 96 tests, Quantitative

MIL-025-170 1 kit
EUR 607.2

Mouse IL-27 ELISA Kit, 96 tests, Quantitative

MIL-027-175 1 kit
EUR 607.2

Mouse IL-33 ELISA Kit, 96 tests, Quantitative

MIL-033-180 1 kit
EUR 607.2

Human IL-10 ELISA Kit, 96 tests, Quantitative

HIL-010-120 1 kit
EUR 578.4

Human IL-13 ELISA Kit, 96 tests, Quantitative

HIL-013-130 1 kit
EUR 607.2

Human IL-15 ELISA Kit, 96 tests, Quantitative

HIL-015-135 1 kit
EUR 607.2

Human IL-21 ELISA Kit, 96 tests, Quantitative

HIL-021-145 1 kit
EUR 578.4

Human IL-22 ELISA Kit, 96 tests, Quantitative

HIL-022-150 1 kit
EUR 607.2

Human IL-23 ELISA Kit, 96 tests, Quantitative

HIL-023-155 1 kit
EUR 607.2

Human IL-27 ELISA Kit, 96 tests, Quantitative

HIL-027-160 1 kit
EUR 607.2

Human IL-29 ELISA Kit, 96 tests, Quantitative

HIL-029-165 1 kit
EUR 578.4

Human Estrone ELISA Kit, 96 tests, Quantitative

1925 1 kit
EUR 708

Rat Clusterin ELISA kit 96 tests, Quantitative

610-110-RCL 1 Kit
EUR 927.6

Rat Hemopexin ELISA kit 96 tests, Quantitative

610-710-HPX 1 Kit
EUR 927.6

Mouse Albumin ELISA Kit, 96 tests, Quantitative

6300 1 kit
EUR 854.4

Pig Myoglobin ELISA kit 96 tests, Quantitative

600-640-PMY 1 Kit
EUR 1000.8

Rat Myoglobin ELISA kit 96 tests, Quantitative

600-660-RMY 1 kit
EUR 1000.8

Human Glucose ELISA Kit, 96 tests, Quantitative

9575 1 Kit
EUR 927.6

Sheep IgG-Fc ELISA Kit, 96 tests, Quantitative

7615-Fc 1 kit
EUR 854.4

Horse IgG-Fc ELISA Kit, 96 tests, Quantitative

7715-Fc 1 kit
EUR 854.4

Mouse GM-CSF ELISA Kit, 96 tests, Quantitative

MGM-CSF-100 1 kit
EUR 578.4

Mouse IL-17F ELISA Kit, 96 tests, Quantitative

MIL-017-140 1 kit
EUR 607.2

Mouse IL-17A ELISA Kit, 96 tests, Quantitative

MIL-17A-185 1 kit
EUR 578.4

Human GM-CSF ELISA Kit, 96 tests, Quantitative

HGM-CSF-100 1 kit
EUR 578.4

Human IL-17A ELISA Kit, 96 tests, Quantitative

HIL-17A-175 1 kit
EUR 578.4

Human IL-17F ELISA Kit, 96 tests, Quantitative

HIL-17F-185 1 kit
EUR 607.2

Corticosterone ELISA Kit, 96 tests, Quantitative

CRS-100 1 kit
EUR 854.4

Alpha-Fetoprotein, AFP ELISA Kit (Quantitative)

DEIA080 96T
EUR 602.4
Description: This AFP ELISA kit is an enzyme linked immunosorbent assay (ELISA) for in vitro quantitative determination of α-fetoprotein (AFP) concentrations in the range of 2-400ng/mL in human serum or plasma samples.

Goat Prolactin ELISA Kit, 96 tests, Quantitative

10735 1 Kit
EUR 927.6

Human Cortisol ELISA Kit, 96 tests, Quantitative

1850 1 kit
EUR 634.8

Monkey Albumin ELISA Kit, 96 tests, Quantitative

7000-10 1 Kit
EUR 927.6

Rat Thiostatin ELISA kit 96 tests, Quantitative

600-730-RTS 1 Kit
EUR 927.6

Human Thrombin ELISA Kit, 96 tests, Quantitative

9625 1 Kit
EUR 927.6

Mouse Ferritin ELISA Kit, 96 tests, Quantitative

9320 1 Kit
EUR 927.6

Mouse Glucagon ELISA Kit, 96 tests, Quantitative

9335 1 Kit
EUR 1074

Rat IL-1 beta ELISA Kit, 96 tests, Quantitative

RIL-01B-100 1 kit
EUR 578.4

Lipoxin A4 (LXA4) ELISA Kit, 96 tests, Quantitative

10885 1 Kit
EUR 927.6

Sheep/Ovine Fab ELISA Kit, 96 tests, Quantitative

7610-Fab 1 kit
EUR 854.4

Mouse IL-17AF ELISA Kit, 96 tests, Quantitative

MIL-17AF-190 1 kit
EUR 578.4

Human IL-17AF ELISA Kit, 96 tests, Quantitative

HIL-17AF-180 1 kit
EUR 607.2

Protein-G (HCPs) ELISA Kit, 480 tests, Quantitative

800-120-PRG-5 1 pk
EUR 3714

Quantitative Pipettes Bulb Fillers

PF330 1 UNIT
EUR 66.26

Mouse Myostatin ELISA Kit, 96 tests, Quantitative

100-220-MYM 1 Kit
EUR 1000.8

Hyaluronic Acid ELISA Kit, 96 tests, Quantitative

10850 1 Kit
EUR 927.6

Chicken Insulin ELISA Kit, 96 tests, Quantitative

10655 1 Kit
EUR 927.6

Human Estradiol ELISA Kit, 96 tests, Quantitative

1920 1 kit
EUR 708

Total Bilirubin Assay Kit, Quantitative, 96 tests

BBN-100 1 kit
EUR 854.4

Human Neopterin ELISA Kit, 96 tests, Quantitative

3410 1 kit
EUR 854.4

Dog Transferrin ELISA Kit, 96 tests, Quantitative

400-195-DGT 1 Kit
EUR 854.4

Mouse Clusterin ELISA kit 96 tests, Quantitative

610-100-MCL 1 Kit
EUR 927.6

Dog Haptoglobin ELISA kit, 96 tests, Quantitative

6250-10 1 kit
EUR 927.6

Rat Haptoglobin ELISA kit 96 tests, Quantitative

6250-30 1 Kit
EUR 927.6

Pig Haptoglobin ELISA kit 96 tests, Quantitative

6250-40 1 Kit
EUR 927.6

Cat Haptoglobin ELISA kit 96 tests, Quantitative

6250-50 1 Kit
EUR 927.6

Human Myoglobin ELISA kit 96 tests, Quantitative

600-610-HMY 1 Kit
EUR 1000.8

Mouse Myoglobin ELISA kit 96 tests, Quantitative

600-630-MMY 1 Kit
EUR 1000.8

Monkey Thrombin ELISA Kit, 96 tests, Quantitative

9730 1 Kit
EUR 927.6

Human VEGFR2/KDR ELISA Kit, 96 tests, quantitative

200-860-KDR 1 kit
EUR 1000.8

Protein-G (HCPs) ELISA Kit, 96 tests, Quantitative

800-120-PRG 1 Kit
EUR 927.6

Peroxide Quantitative Assay Kit (Water compatible)

BSP069 250Assays, 250preps
EUR 110.11

Human Angiogenin ELISA Kit, 96 tests, Quantitative

100-160-ANH 1 Kit
EUR 854.4

Monkey Myoglobin ELISA kit 96 tests, Quantitative

600-620-MMY 1 Kit
EUR 1000.8

Rabbit Myoglobin ELISA kit 96 tests, Quantitative

600-650-RMY 1 Kit
EUR 1000.8

Mouse Creatinine ELISA Kit, 96 tests, Quantitative

9255 1 Kit
EUR 927.6

Mouse IL-1 beta ELISA Kit, 96 tests, Quantitative

MIL-01B-150 1 kit
EUR 578.4

Human IL-12 p70 ELISA Kit, 96 tests, Quantitative

HIL-012-125 1 kit
EUR 578.4

Human IL-1 beta ELISA Kit, 96 tests, Quantitative

HIL-01B-140 1 kit
EUR 578.4

Mouse TNF-alpha ELISA Kit, 96 tests, Quantitative

100-210-TNF 1 kit
EUR 578.4

Human TNF-alpha ELISA Kit, 96 tests, Quantitative

100-215-TNH 1 kit
EUR 578.4

Mouse Granzyme B ELISA Kit, 96 tests, Quantitative

MGB-100 1 kit
EUR 607.2

Rabbit Calcitonin ELISA Kit, 96 tests, Quantitative

10550 1 Kit
EUR 927.6

Canine Fibrinogen ELISA Kit, 96 tests, Quantitative

10430 1 Kit
EUR 927.6

3-Nitrotyrosine ELISA Kit, 96 tests, Quantitative

10855 1 Kit
EUR 927.6

Sheep Haptoglobin ELISA Kit, 96 tests, Quantitative

10595 1 Kit
EUR 927.6

Human Aldosterone ELISA Kit, 96 tests, Quantitative

1875 1 kit
EUR 634.8

Mouse Haptoglobin ELISA kit 96 tests, Quantitative

6250 1 kit
EUR 927.6

Horse Haptoglobin ELISA kit 96 tests, Quantitative

6250-20 1 kit
EUR 927.6

Sheep Lactoferrin ELISA Kit, 96 tests, Quantitative

8095 1 kit
EUR 1220.4

Szacowanie skuteczności rutynowych bezobjawowych testów PCR z różnymi częstotliwościami w celu wykrycia zakażeń SARS-CoV-2 

Background: Routine asymptomatic testing utilizing RT-PCR of people that work together with weak populations, comparable to medical workers in hospitals or care staff in care properties, has been employed to assist stop outbreaks amongst weak populations. Though the height sensitivity of RT-PCR could be excessive, the chance of detecting an an infection will range all through the course of an an infection. The effectiveness of routine asymptomatic testing will subsequently depend upon testing frequency and the way PCR detection varies over time.

Strategies: We fitted a Bayesian statistical mannequin to a dataset of twice weekly PCR exams of UK healthcare staff carried out by self-administered nasopharyngeal swab, no matter signs. We collectively estimated instances of an infection and the chance of a optimistic PCR take a look at over time following an infection; we then in contrast asymptomatic testing methods by calculating the chance {that a} symptomatic an infection is detected earlier than symptom onset and the chance that an asymptomatic an infection is detected inside 7 days of an infection.

Outcomes: We estimated that the chance that the PCR take a look at detected an infection peaked at 77% (54-88%) four days after an infection, reducing to 50% (38-65%) by 10 days after an infection. Our outcomes counsel a considerably greater chance of detecting infections 1-Three days after an infection than beforehand printed estimates. We estimated that testing each different day would detect 57% (33-76%) of symptomatic instances previous to onset and 94% (75-99%) of asymptomatic instances inside 7 days if take a look at outcomes have been returned inside a day.

Conclusions: Our outcomes counsel that routine asymptomatic testing can allow detection of a excessive proportion of contaminated people early of their an infection, offered that the testing is frequent and the time from testing to notification of outcomes is sufficiently quick.

Zintegrowany system Argonaute do PCR z pojedynczą probówką umożliwia bardzo czułe wykrywanie rzadkich mutacji 

Technological advances in uncommon DNA mutations detection have revolutionized the analysis and monitoring of tumors, however they’re nonetheless restricted by the shortage of supersensitive and high-coverage procedures for figuring out low-abundance mutations. Right here, we describe a single-tube, multiplex PCR-based system, A-Star, that includes a hyperthermophilic Argonaute from Pyrococcus furiosus (PfAgo) for extremely environment friendly detection of uncommon mutations useful from its compatibility with DNA polymerase. This novel method makes use of a selected information design technique to permit PfAgo selective cleavage with single-nucleotide decision at 94°C, thus principally eliminating wild-type DNA within the denaturation step and effectively amplifying uncommon mutant DNA in the course of the PCR course of.

The built-in single-tube system achieved nice effectivity for enriching uncommon mutations in contrast with a divided system separating the cleavage and amplification. Thus, A-Star permits simple detection and quantification of 0.01% uncommon mutations with ≥5500-fold improve in effectivity. The feasibility of A-Star was additionally demonstrated for detecting oncogenic mutations in strong tumor tissues and blood samples. Remarkably, A-Star achieved simultaneous detection of a number of oncogenes by a easy single-tube response by orthogonal guide-directed particular cleavage. This examine demonstrates a supersensitive and fast nucleic acid detection system with promising potential for each analysis and therapeutic purposes.

Pacjenci z dodatnim wynikiem testu COVID19-PCR jako negatywna kontrola testów na obecność przeciwciał COVID19 

  • COVID-19 serological antibody exams are lately wanted for a comparatively fast, inexpensive, and priceless evaluation of the immunity towards COVID-19 an infection. Moreover, they may also help with evaluating the sufficiency of the vaccination course of and its longevity. There are limitations within the present method of selecting the optimistic and destructive management samples for the validation of these exams.
  • Herein, we’re proposing using blood samples from optimistic COVID-19 sufferers, initially of the illness course, as destructive management blood samples for the antibody exams. For extra precision, each the destructive and the optimistic management samples could be obtained from the identical sufferers the place the accuracy of the take a look at will depend upon its means to detect the seroconversion, from destructive to optimistic antibodies detection, inside the identical affected person.
  • Moreover, when the validation of the take a look at is accompanied by detecting/sequencing the viral genome in these COVID-19 sufferers, this could additionally help in figuring out the accuracy of the take a look at in detecting the immune response to particular viral variants. The latter notion is required for the right administration of the COVID-19 disaster, new vaccines’ manufacturing, and evaluating the vaccines’ efficiencies. Lastly, this method could possibly be requested/formulated by the regulatory companies as a part of the exams’ validation and could be “in-house” obtained by well being amenities earlier than its scientific use.

Systematyczny przegląd i metaanaliza wypisanych pacjentów COVID-19 z dodatnim wynikiem RT-PCR 

Background: With the elevated variety of sufferers discharged after having COVID-19, increasingly research have reported instances whose retesting was optimistic (RP) throughout the convalescent interval, which brings a brand new public well being problem to the world.

Strategies: We searched PubMed, Net of Science, The Cochrane Library, CNKI, WanFang and VIP from December 1, 2019 to December 31, 2020. The included research have been assessed utilizing JBI vital appraisal instruments and Newcastle-Ottawa Scale. The RP fee of discharge sufferers was analyzed by a meta-analysis. We adhered to PRISMA reporting guideline.

Findings: We’ve got included 117 research with 2669 RP contributors after discharge. The methodological high quality of 66 case studies have been low to excessive, 42 case sequence and three cohort examine have been average to excessive, Three case-control research have been average and three cross-sectional research have been low to average. The scientific manifestations of most RP sufferers have been delicate or asymptomatic, and CT imaging and laboratory examinations have been normally regular. The present danger components counsel that extra consideration needs to be paid to sever sufferers, aged sufferers, and sufferers with co-morbidities. The abstract RP fee was 12·2% (95% CI 10·6-13·7) with excessive heterogeneity (I2 = 85%).

Interpretation: To this point, the causes and danger components of RP lead to discharged sufferers usually are not totally understood. Excessive-quality etiological and scientific research are wanted to research these points to additional assist us to make methods to manage and forestall its prevalence.

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